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Molecule Focus: Bispecific Antibody (BsAb) - Explore All BsAb Resources in One Convenient Hub 

27-05-2025 04:55 PM

As of 2025, the bispecific antibody (BsAb) market exceeds USD 10 billion, fueled by multiple FDA approvals and 300+ clinical candidates. BsAbs now go beyond T-cell engagers to include NK cell engagers, dual checkpoint inhibitors, receptor clustering agents, and tumor-targeted cytokines, with formats ranging from IgG-like to trispecific and Fc-silent designs. 
 
With innovation spanning discovery, process development, and manufacturing, understanding the full bsAb development continuum is critical. For scientists, developers, and decision-makers, learning this integrated landscape is essential to reduce R&D risk, accelerate timelines, and capture opportunity in one of the most competitive and transformative biologics sectors today.

  

🔬What to Learn:
 
1. Start Strong with BsAb Discovery
White Paper: How to Design and Evaluate BsAbs
  • What are BsAbs?
  • How to design discovery strategies based on structure?
  • How to evaluate BsAbs comprehensively by MOA?
 
2. Reliable Cell line development
Poster: Optimized Vector System for BsAb Expression in CHO-K1 Cells
White Paper: Cell Line Development Strategies for BsAb Manufacturing
 
3. Accelerated CMC Development
Folding: From Sequence to Tox DS Release in 7 Months for Symmetrical BsAb
White paper: Analytical Approach for BsAb Quality Study
 
4. Smooth tech transfer and qualified manufacturing
Handbook: Tech Transfer Manual
Folding: GMP Manufacturing Solutions
 
5. Proven Success
By providing a comprehensive suite of CMC development and IND dossier services, ProBio supported IMBiologics in obtaining FDA clearance and achieving a smooth license-out.
  • 2023 ProBio Congratulates IMBiologics on FDA Clearance of IND Application for Innovative Bispecific Antibody Drug Project (IMB-101)
  • 2024 IMBiologics Licenses $925mn Antibody Treatment (IMB-101) to Navigator Medicines
 
6. On-demand webinar
  • Multiple Solutions of Functional Leads Discovery and Engineering
  • ProBox™ Platform for Complex Biologics CMC Development
  • Navigating Biologics Challenges:Regulatory, Process Development, and Tech Transfer Solutions 
 

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