Sub-Investigator

General role description

Sub-Investigators (Sub-Is) play an essential role in the delivery of clinical trials, working under the direction of the Principal Investigator (PI) to support all aspects of trial conduct. This includes screening and enrolling participants, conducting medical assessments, obtaining informed consent, and documenting and reporting adverse events. Sub-Is help ensure adherence to trial protocols, Good Clinical Practice (GCP), and all applicable regulatory requirements. These roles are typically held by registered medical practitioners working in hospital, private practice, or research settings, and offer a valuable pathway for clinicians seeking involvement in clinical research.

Key tasks and responsibilities

  • Screen and enrol trial participants
  • Conduct medical assessments and obtain informed consent
  • Document and report adverse events
  • Ensure adherence to trial protocols and GCP standards
  • Collaborate with Principal Investigator and trial team

Workplace settings

  • Hospitals and healthcare services
  • Private practice settings involved in clinical trials
  • Research institutes running clinical research

Required qualifications

  • Medical degree and full registration with AHPRA
  • Good Clinical Practice (GCP) certification (or willingness to obtain)

Other notable requirements

  • Experience in patient care, clinical assessment, or general practice
  • Understanding of clinical research protocols and safety reporting
  • Strong attention to detail and documentation skills
  • Clear and professional communication with participants and trial teams
  • Ability to work under the supervision of a Principal Investigator and collaborate within a trial team

Common entry points

Healthcare setting-based doctors contributing to research studies as part of clinical duties

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