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White Paper: Challenges and Solutions in the Development of High-concentration Protein Formulations

  • 1.  White Paper: Challenges and Solutions in the Development of High-concentration Protein Formulations

    Posted 14-04-2025 05:28 PM

    As biomedicine advances and market demands evolve, high-concentration protein formulations (HCPF) are gaining increasing prominence in the biopharmaceutical industry. However, developing these formulations presents several challenges. Drawing on extensive experience in biologics development, ProBio has created a formulation platform that optimizes and accelerates the development process.

    This white paper explores solutions to the following key challenges in high-concentration protein formulation:

    • Viscosity
    • Aggregation
    • Surfactant degradation
    • Long reconstitution time
    • pH drift
    • UF/DF risks
    • Big variation in concentration measurement

    Free download



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    Jessica Tu
    Regional Marketing Manager
    ProBio
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